Recombinant Penetratin-Cre recombinase (Penetratin-Cre) was purified from an E. coli strain carrying an engineered plasmid encoding Cre Recombinase from bacteriophage P1 with additional N-terminal 6XHis tag and a cell permeable Penetratin (RGIKWFGNRRMKWKK) and an NLS sequence (PKKKRKV). This cell-permeant Cre recombinase is effective in transduction and subsequent recombination in various cell types.
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