| Product Name |
Murine Leukemia Virus (MLV)Pseudotyped with SARS-CoV-2
Spike Glycoprotein, HexaPro Stabilized Trimer
|
| Description |
Murine leukemia retrovirus (MLV) particles
pseudotyped with SARS-CoV-2
spike glycoprotein, with hexaPro mutations so the surface protein antigenically optimal pre-fusion conformation, produced and purified from HEK 293 cells
|
| Mutations |
Furin site RRAR mutated to GSAS; HexaPro mutations (K986P, V987P, F817P, A892P, A899P and A942P) to ensure the S glycoprotein remains in an antigenically optimal pre-fusion conformation
|
| Source
|
HEK293T cells
|
| Reporter
|
EGFP
|
| Application |
- Screening of SARS-CoV-2
neutralizing antibodies
-
Assessment of vaccine efficacy
|
| Titer |
> 1 X 107 RFU/ml or > 1 X 105 TU/ml
|
| Shipping |
Dry ice |
| Storage |
-80 oC |
| References
|
|