mRNA Cap 2‘-O-Methyltransferase, Animal-Free

Cat #: EG-2753

Qty

Product Name	mRNA Cap 2'-O-Methyltransferase
Catalog #	EG-2753
Description	mRNA Cap 2'-O-Methyltransferase catalyzes the methylation of the ribose 2'-hydroxyl group of the first transcribed nucleotide (Cap 0) using S-adenosylmethionine (SAM) as the methyl donor, converting it to a 2'-O-methylated cap structure (Cap 1). The addition of a Cap 1 structure enhances mRNA translation efficiency and reduces recognition by innate immune sensors in mammalian cells. This enzyme is purified from an E. coli strain engineered to overexpress the vaccinia virus PAPS gene.
Size	2000 units
Applications	Generation of Cap 1 structures on in vitro transcribed mRNA in the presence of GTP and SAM.
Storage	-80 °C